HSSH-model of Hole transfer in DNA

  • V. D. Lakhno
  • N. S. Fialko
Statistical Physics and Biological Information


A method based on a selfconsistent solution of a quantum-mechanical system with temperature fluctuations described by Langevin equations is developed to calculate the charge carrier mobility in DNA. To model the charge transfer in DNA, a combined Holstein – SSH Hamiltonian is considered. As an example the hole mobility is calculated at room temperature for synthetic poly (G)/poly (C) duplex with regard to main structural fluctuations.


Spectroscopy Neural Network State Physics Charge Transfer Complex System 
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© EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2005

Authors and Affiliations

  1. 1.Institute of Mathematical Problems of Biology, Russian Academy of SciencesMoscow RegionRussian Federation

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