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Mycobacterium tuberculosis: Strategies of offense and defense

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Abstract

Strategies of macrophage attack by Mycobacterium tuberculosis and defense against immune response are considered in detail. The mechanisms of cell invasion, strategies of survival within phagosomes, methods for the suppression of antigen presentation, and pathways of M. tuberculosis transition into the persisting latent state are discussed.

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Authors and Affiliations

  1. Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, pr. Lavrentyeva 10, Novosibirsk, 630090, Russia

    S. M. Rozov & E. V. Deineko

  2. Tomsk State University, pr. Lenina 36, Tomsk, 634050, Russia

    E. V. Deineko

  3. Novosibirsk State University, ul. Pirogova 2, Novosibirsk, 630090, Russia

    S. M. Rozov

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Original Russian Text © S.M. Rozov, E.V. Deineko, 2016, published in Uspekhi Sovremennoi Biologii, 2016, Vol. 136, No. 1, pp. 25–40.

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Rozov, S.M., Deineko, E.V. Mycobacterium tuberculosis: Strategies of offense and defense. Biol Bull Rev 6, 276–288 (2016). https://doi.org/10.1134/S2079086416040058

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