Biology Bulletin Reviews

, Volume 6, Issue 4, pp 276–288 | Cite as

Mycobacterium tuberculosis: Strategies of offense and defense

  • S. M. Rozov
  • E. V. Deineko


Strategies of macrophage attack by Mycobacterium tuberculosis and defense against immune response are considered in detail. The mechanisms of cell invasion, strategies of survival within phagosomes, methods for the suppression of antigen presentation, and pathways of M. tuberculosis transition into the persisting latent state are discussed.


intracellular pathogens macrophages phagocytosis interaction with receptors phagosome maturation persistence 


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  1. 1.Institute of Cytology and Genetics, Siberian BranchRussian Academy of SciencesNovosibirskRussia
  2. 2.Tomsk State UniversityTomskRussia
  3. 3.Novosibirsk State UniversityNovosibirskRussia

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