Russian Journal of Genetics: Applied Research

, Volume 6, Issue 6, pp 657–668 | Cite as

Transgenic farm animals: the status of research and prospects

  • N. A. Zinovieva
  • N. A. Volkova
  • V. A. Bagirov
  • G. Brem


The production of transgenic animals is of great interest for current basic and applied research. This article is a review of methods for the production of transgenic farm animals and their advantages and disadvantages. The advances in various fields of genetic engineering of domestic animals are discussed, including the creation of animals with altered metabolism for higher quality and productivity, animals genetically resistant to infectious diseases, producers of biologically active recombinant proteins, donors of organs for human transplantation (xenotransplantation), and animal models.


recombinant DNA transgenesis genetically modified farm animals animal bioreactors 


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • N. A. Zinovieva
    • 1
  • N. A. Volkova
    • 1
  • V. A. Bagirov
    • 1
  • G. Brem
    • 2
  1. 1.Ernst Institute for Animal HusbandryDubrovitsy, Moscow oblastRussia
  2. 2.Institute for Animal Breeding and Genetics, VMUViennaAustria

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