Evolution of multigene families are considered in the review on the example of the PHO gene family encoding the structure of acid phosphatases in the yeast Saccharomyces cerevisiae. Analysis of the databases demonstrated that divergence due to a change in regulation of the structural genes and their inclusion in new regulatory networks is the main direction of evolution of multigene families encoding exoenzymes.
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Original Russian Text © E.V. Sambuk, M.V. Padkina, 2013, published in Ekologicheskaya Genetika, 2013, Vol. 11, No. 4, pp. 34–44.
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Sambuk, E.V., Padkina, M.V. Divergence of expression of PHO3, PHO5, PHO11, and PHO12 paralogs in the yeast Saccharomyces cerevisiae is a mechanism of evolution of multigene families. Russ J Genet Appl Res 5, 82–90 (2015). https://doi.org/10.1134/S2079059715020100
- acid phosphatase
- multigene families
- expression of genes
- evolution of duplicated genes