Skip to main content
Log in

Mitochondrial DNA diversity in the gene pool of the Neolithic and Early Bronze Age Cisbaikalian human population

  • Published:
Russian Journal of Genetics: Applied Research

Abstract

This paper presents the results of a study of a mitochondrial DNA sample (N = 15) from the remains of representatives of the Neolithic and Early Bronze Age (VI–III millennia BC) Cisbaikalian human population. It was found that the mitochondrial gene pool of the ancient population under study contains lineages of East Eurasian haplogroups D, G2a C, Z, and F1b. The results of the comparative analysis of the group under study with ancient and modern Eurasian populations suggest that the development of autochtonous East Eurasian genetic components was the main mechanism of the formation of the population of the Baikal region. Genetic contacts with populations of neighboring regions of Central Asia also contributed to the formation of the gene pool of the Cisbaikalian population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Alekseev, V.P., Antropologicheskie tipy Yuzhnoi Sibiri (Sayano-Altaiskoe nagor’e) v epokhu neolita i bronzy. Voprosy istorii Sibiri i Dal’nego Vostoka (Anthropological Types of Southern Siberia (Sayan-Altai Mountains) in the Neolithic and Bronze Age. Problems of History of Siberia and the Far East), Novosibirsk: SO AN SSSR, 1961.

    Google Scholar 

  • Alekseev, V.P., Geografiya chelovecheskikh ras (Geography of Human Races), Moscow: Mysl’, 1974.

    Google Scholar 

  • Andrews, R.M., Kubacka, I., Chinneryp, F., Lightowlers, R.N., Turnbull, D.M., and Howell, N., Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA, Nat. Genet., 1999, vol. 23, p. 147.

    Article  CAS  PubMed  Google Scholar 

  • Bramanti, B., Thomas, M.G., Haak, W., Unterlaender, M., Jores, P., Tambets, K., Antanaitis-Jacobs, I., Haidle, M.N., Jankauskas, R., Kind, C.-J., Lueth, F., Terberger, T., Hiller, J., Matsumura, S., Forster, P., and Burger, J., Genetic discontinuity between local hunter-gatherers and Central Europe’s first farmers, Science, 2009, vol. 326, no. 326, pp. 137–140.

    Article  CAS  PubMed  Google Scholar 

  • Comas, D., Calafell, F., Mateu, E., Perez-Lezaun, A., Bosch, E., Bosch, E., Martinez-Arias, R., Clarimon, J., Facchini, F., Fiori, G., Luiselli, D., Pettener, D., and Bertranpetit, J., Trading genes along the Silk Road: mtDNA sequences and the origin of Central Asian populations, Am. J. Hum. Genet., 1998, vol. 63, pp. 1824–1838.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Debets, G.F., Paleoantropologiya SSSR (Paleoanthropology of the USSR), Moscow: Izd. AN SSSR, 1948.

    Google Scholar 

  • Debets, G.F., Population of Southern and Western Asia according to anthropology, in Proiskhozhdenie cheloveka i drevnee rasselenie chelovechestva (The Origin of Man and the Ancient Radiation of Mankind), Moscow: Izd. AN SSSR, 1951, vol. 16, pp. 355–370.

    Google Scholar 

  • Derenko, M.V., Grzybowski, T., Malyarchuk, B.A., Dambueva, I.K., Denisova, G.A., Czarny, J., Dorzhu, C.M., Kakpakov, V.T., Miscicka-Sliwka, D., Wozniak, M., and Zakharov, I.A., Diversity of mitochondrial DNA lineages in South Siberia, Ann. Hum. Genet., 2003, vol. 67, pp. 391–411.

    Article  CAS  PubMed  Google Scholar 

  • Derenko, M.V., Lunkina, A.V., Malyarchuk, B.A., Zakharov, I.A., Tsedev, T.S., Parkk, S., Cho, Y.M., Lee, H.K., and Chu, Ch.H., Restriction polymorphism of mitochondrial DNA in Koreans and Mongolians, Russ. J. Genet, 2004, vol. 40, pp. 1562–1570.

    Article  CAS  Google Scholar 

  • Derenko, M., Malyarchuk, B., Grzybowski, T., Denisova, G., Dambueva, I., Perkova, M., Dorzhu, C., Luzina, F., Lee, H.K., Vanecek, T., Villems, R., Zakharov, I., Phylogeographic analysis of mitochondrial DNA in Northern Asian populations, Am. J. Hum. Genet., 2007, vol. 81, pp. 1025–1041.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Derenko, M., Malyarchuk, B., Grzybowski, T., Denisova, G., Rogalla, U., Perkova, M., Dambueva, I., and Zakharov, I., Origin and post-glacial dispersal of mitochondrial DNA of haplogroups C and D in Northern Asia, PLoS One, 2010, vol. 5, no. 12, p. e15214.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Excoffier, L., Laval, G., and Schneider, S., Arlequin ver. 3.0: an integrated software package for population genetics data analysis, Evol. Bioinform. Online, 2005, vol. 1, pp. 47–50.

    PubMed Central  CAS  Google Scholar 

  • Gerasimov, M.M., Paleolithic site Mal’ta (excavations of 1956–1957), in Sov. etnografiya (Soviet Ethnography), Moscow: Izd. AN SSSR, 1958, vol. 3, pp. 28–52.

    Google Scholar 

  • Gubina, M.A., Osipova, L.P., and Villems, R., Analysis of maternal gene pool for mitochondrial DNA polymorphism in populations of the Khanty and Komi of Shuryshkarskii District of the Yamal-Nenets Autonomous Area, in Korennoe naselenie Shuryshkarskogo raiona Yamalo-Nenetskogo avtonomnogo okruga: demograficheskie, geneticheskie i meditsinskie aspekty (Indigenous People of the Shuryshkarskii District of the Yamalo-Nenets Autonomous Area: Demographic, Genetic, and Medical Aspects), Novosibirsk, 2005, pp. 105–117.

    Google Scholar 

  • Haak, W., Forster, P., Bramanti, B., Matsumura, S., Brandt, G., Tanzer, M., Villems, R., Renfrew, C., Gronenborn, D., Alt, K.W., and Burger, J., Ancient DNA from the first European farmers in 7500-year-old neolithic sites, Science, 2005, vol. 305, pp. 1016–1018.

    Google Scholar 

  • Keyser-Tracqui, C., Crubezy, E., and Ludes, B., Nuclear and mitochondrial DNA analysis of a 2.000 year-old necropolis in the Egyin Gol valley of Mongolia, Am. J. Hum. Genet., 2003, vol. 73, pp. 247–260.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Kloss-Brandstatter, A., Pacher, D., Schonherr, S., Weissensteiner, H., Binna, R., Specht, G., and Kronenberg, F., HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups, Hum. Mutat., 2011, vol. 32, pp. 25–32.

    Article  PubMed  Google Scholar 

  • Kolman, C.J., Sambuughin, M., and Bermingham, E., Mitochondrial DNA analysis of Mongolian population and implications for the origin of new world founders, Genetics, 1996, vol. 142, no. 4, pp. 1321–1334.

    PubMed Central  CAS  PubMed  Google Scholar 

  • Malyarchuk, B.A., Grzybowski, T., Czarny, J., Wozniak, M., and Miscicka-Sliwka, D., Mitochondrial DNA variability in Poles and Russians, Ann. Hum. Genet., 2002, vol. 66, pp. 261–283.

    Article  CAS  PubMed  Google Scholar 

  • Metspalu, M., Kivisild, T., Metspalu, E., Parik, J., Hudjashov, G., Kaldma, K., Serk, P., Karmin, M., Behar, D.M., Gilbert, M.T.P., Endicott, P., Mastana, S., Papiha, S.S., Skorecki, K., Torroni, A., and Villems, R., Most of the extant mtDNA boundaries in South and Southwest Asia were likely shaped during the initial settlement of Eurasia by anatomically modern humans, BMC Genetics, 2004, vol. 5, p. 26.

    Article  PubMed Central  PubMed  Google Scholar 

  • Molodin, V.I., Pilipenko, A.S., Romaschenko, A.G., Zhuravlev, A.A., Trapezov, R.O., Chikisheva, T.A., and Pozdnyakov, D.V., Human migrations in the southern region of the West Siberian Plain during the Bronze Age: archaeological, palaeogenetic and anthropological data, in Population Dynamics in Prehistory and Early History: New Approaches Using Stable Isotopes and Genetics, Kaiser, E., Burger, J., and Schier, W., Eds., Berlin: De Gruyter, 2012, pp. 95–113.

    Google Scholar 

  • Mooder, K.P., Schurr, T.G., Bamforth, F.J., Bazaliiski, V.I., and Savel’ev, N.A., Population affinities of neolithic siberians: a snapshot from prehistoric Lake Baikal, Am. J. Phys. Anthropol., 2006, vol. 129, pp. 349–361.

    Article  CAS  PubMed  Google Scholar 

  • Naumova, O.Yu., Rychkov, S.Yu., Morozova, I.Yu., Khayat, S.Sh., Semikov, A.V., and Zhukova, O.V., Mitochondrial DNA diversity in Siberian Tatars of the Tobol-Irtysh basin, Russ. J. Genet., 2008, vol. 44, no. 2, pp. 215–226.

    Article  CAS  Google Scholar 

  • Okladnikov, A.P., Paleoliticheskie zhilishcha v Bureti (po raskopkam 1936–1940 gg.), Kratkie Soobshcheniya Inta istorii material’noi kul’tury, 1941, no. 10, pp. 16–31.

    Google Scholar 

  • Okladnikov, A.P., Neolit i bronzovyi vek Pribaikal’ya: Istoriko-arkheologicheskoe issledovanie (Neolithic and Bronze Age Baikal Region: Historical and Archaeological Research), Ch. I, Ch. II, Materialy i issledovaniya po arkheologii SSSR. no. 18 (Materials and Research on the Archeology of the USSR, No. 18), Moscow: Izd. AN SSSR, 1950.

    Google Scholar 

  • Okladnikov, A.P., Neolit i bronzovyi vek Pribaikal’ya: Glazkovskoe vremya (Neolithic and Bronze Age of Cisbaikalia: Glazkov Time), Ch. III, Materialy i issledovaniya po arkheologii SSSR. no. 43 (Materials and Research on the Archeology of the USSR, No. 43), Moscow: Izd. AN SSSR, 1955.

    Google Scholar 

  • van Oven, M. and Kayser, M., Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation, Hum. Mutat., 2009, vol. 30, pp. 386–394.

    Article  Google Scholar 

  • Pilipenko, A.S., Romashchenko, A.G., and Molodin, V.I., Kuli-kov I.V., Kobzev V.F., Pozdnyakov D.V., Novikova O.I. Characteristics of burying babies in homes of the Chicha-I settlement of the Baraba forest-steppe according to the DNA structure analysis, Arkheol. Etnogr. Antropol. Evrazii, 2008, no. 2, pp. 57–67.

    Google Scholar 

  • Pilipenko, A.S., Romaschenko, A.G., Molodin, V.I., Parzinger, H., and Kobzev, V.F., Mitochondrial DNA studies of the Pazyryk people (4th to 3rd centuries BC) from northwestern Mongolia, Archaeol. Anthropol. Sci., 2010, vol. 2, pp. 231–236.

    Article  Google Scholar 

  • Pilipenko, A.S., Molodin, V.I., and Romashchenko, A.G., Mitochondrial DNA of a Late Neolithic woman from Kaminnaia cave (Gorny Altai), Russ. J. Genet.: Appl. Res., 2012, vol. 2, no. 3, pp. 214–221.

    Article  Google Scholar 

  • Raghavan, M., Skoglund, P., Graf, K.E., Metspalu, M., Albrechtsen, A., Moltke, I., Rasmussen, S., Stafford, T.W., Jr., Orlando, L., Metspalu, E., Karmin, M., Tambets, K., Rootsi, S., Magi, R., Campos, P.F., Balanovska, E., Balanovsky, O., Khusnutdinova, E., Litvinov, S., Osipova, L.P., Fedorova, S.A., Voevoda, M.I., Degiorgio, M., Sicheritz-Ponten, T., Brunak, S., Demeshchenko, S., Kivisild, T., Villems, R., Nielsen, R., Jakobsson, M., and Willerslev, E., Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans, Nature, 2014, vol. 505, no. 7481, pp. 87–91.

    Article  PubMed Central  PubMed  Google Scholar 

  • Sarkissian, C.D., Balanovsky, O., Brandt, G., Khartanovich, V., Buzhilova, A., Koshel, S., Zaporozhchenko, V., Gronenborn, D., Moiseyev, V., Kolpakov, E., Shumkin, V., Alt, K.W., Balanovska, E., Cooper, A., and Haak, W., The genographic consortium. Ancient DNA reveals prehistoric gene-flow from Siberia in the complex human population history of North East Europe, PLoS Gen., 2013, vol. 9, p. e1003296.

    Article  Google Scholar 

  • Slatkin, M., An exact test for neutrality based on the Ewens sampling distribution, Genet. Res., 1994, vol. 64, no. 1, pp. 71–74.

    Article  CAS  PubMed  Google Scholar 

  • Starikovskaya, E.B., Sukernik, R.I., Derbeneva, O.A., Volodko, N.V., Ruiz-Pesini, E., Torroni, A., Brown, M.D., Lott, M.T., Hosseini, S.H., Huoponen, K., and Wallace, D.C., Mitochondrial DNA diversity in indigenous populations of the southern extent of Siberia, and the origins of Native American haplogroups, Ann. Hum. Genet., 2005, vol. 69, pp. 67–89.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Turner, C.G. and Scott, G.R., The dentition of American Indians: evolutionary results and demographic implications following colonization from Siberia, in Handbook of Paleoanthropology, Henke, W., Hardt, T., and Tattersall, I., Eds., 2007, vol. 3, pp. 1901–1942.

    Article  Google Scholar 

  • Yao, Y.G., Kong, Q.P., Bandelt, H.J., Kivisild, T., and Zhang, Y.P., Phylogeographic differentiation of mitochondrial DNA in Han Chinese, Am. J. Hum. Genet., 2002, vol. 70, pp. 635–651.

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Zubov, A.A. and Gokhman, I.I., Some dental data for the Upper Paleolithic site Mal’ta, Vestn. Antropol., 2003, no. 10, pp. 14–23.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to R. O. Trapezov.

Additional information

Original Russian Text © R.O. Trapezov, A.S. Pilipenko, V.I. Molodin, 2014, published in Vavilovskii Zhurnal Genetiki i Selektsii, 2014, Vol. 18, No. 3, pp. 469–477.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Trapezov, R.O., Pilipenko, A.S. & Molodin, V.I. Mitochondrial DNA diversity in the gene pool of the Neolithic and Early Bronze Age Cisbaikalian human population. Russ J Genet Appl Res 5, 26–32 (2015). https://doi.org/10.1134/S2079059715010104

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S2079059715010104

Keywords

Navigation