Selection of new highly active L-alanine producer strains of Brevibacterium flavum and comparison of their activity in alanine synthesis

  • G. Ye. Avetisova
  • L. H. Melkonyan
  • A. Kh. Chakhalyan
  • S. Gh. Keleshyan
  • A. S. Saghyan
Article
  • 27 Downloads

Abstract

New mutants resistant to L-cycloserine and β-chloro-L-alanine and not described previously were obtained from a parental strain Brevibacterium flavum AA5. Their ability to produce alanine was studied. It was found that the resistance to L-cycloserine did not significantly affect the yield of L-alanine, whereas the resistance to β-chloro-L-alanine of B. flavum GL1 and B. flavum GL18 producers exceeded the initial level of the L-alanine synthesis by 23 and 38%, respectively.

Keywords

Brevibacterium flavum mutagenesis producer strain L-alanine 

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Copyright information

© Pleiades Publishing, Ltd. 2014

Authors and Affiliations

  • G. Ye. Avetisova
    • 1
  • L. H. Melkonyan
    • 1
  • A. Kh. Chakhalyan
    • 1
  • S. Gh. Keleshyan
    • 1
  • A. S. Saghyan
    • 1
  1. 1.Scientific and Production Center ArmbiotechnologyNational Academy of Sciences of ArmeniaYerevanArmenia

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