Advertisement

Advances in Gerontology

, Volume 6, Issue 1, pp 52–59 | Cite as

Clinical and pathogenic features of ischemic stroke among representatives of different gender and age groups

  • V. S. Myakotnykh
  • E. Y. Kravtsova
  • G. A. Martynova
  • R. V. Soloviev
  • D. A. Berezina
  • T. A. Borovkova
  • K. V. Myakotnykh
Article

Abstract

A total of 1410 patients with ischemic stroke (IS) of four main clinical and pathogenic subtypes, viz., atherothrombotic, cardioembolic, hemodynamic, and lacunar strokes, were studied. We analyzed the dependence of the pathogenic subtype of the stroke, its background pathologies, and stroke risk factors on the age and gender of the patients. It was found that senior patients were more susceptible to atherothrombotic ischemic strokes and patients of working age more frequently suffered from lacunar and hemodynamic strokes, although cases of atherothrombotic strokes in this age cohort were more often observed in male patients. The significance of arterial hypertension in the development of ischemic stroke decreases with age but the role of cerebral arteriosclerosis, coronary artery disease, and cardiac arrhythmias greatly expands. At retirement age, the prevalent risk factors of ischemic stroke are lack of physical exercise, being overweight, and dyslipidemia, with reducing roles of smoking and stress, which are more relevant to the working ages. The occurrence of particular risk factors and IS background diseases is age specific but in different age periods and for different pathogenic subtypes of ischemic stroke this dependence changes, while at the retirement ages it is less distinct than for the working-age cohort.

Keywords

ischemic stroke background diseases risk factors age gender 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Vereshchagin, N.V., Heterogenety of stroke in clinical ractice, Atmos. Nervn. Bolezni, 2004, no. 1, pp. 19–20.Google Scholar
  2. 2.
    Ershov, V.I. and Burdakov, V.V., Mathematical modeling of acute period of ischemic stroke with different athogenesis, Zh. Nevropatol. Psikhiatr. im. S.S. Korsakova, 2009, vol. 12, no. 2, pp. 13–17.Google Scholar
  3. 3.
    Kravtsova, E.Yu., Martynova, G.A., and Kravtsova, T.Yu., Clinical features of different subtypes of ischemia in working people, Perm. Med. Zh., 2011, vol. 28, no. 4, p. 17–20.Google Scholar
  4. 4.
    Myakotnykh, V.S. and Borovkova, T.A., Ateroskleroticheskie porazheniya u lits pozhilogo i starcheskogo vozrasta, stradayushchikh neiropsikhicheskimi rasstroistvami (Atherosclerotic Diseases of Elderly and Senile eople with Neuropsychical Disorders), Yekaterinburg: Ural. Gos. Med. Akad., 2009.Google Scholar
  5. 5.
    Pyshkina, A.I., Kabanov, A.A., and Alibekova, Zh.M., Demographic features of the structure of risk factors of ischemic stroke in Dagestan Republic, Zh. Nevrol. sikhiatr., 2014, vol. 114, no. 8 (2), pp. 65–68.Google Scholar
  6. 6.
    Simonenko, V.B. and Shirokov, E.A., The concepts of risk factors, Zh. Nevrol. Psikhiatr., 2006, no. 2, pp. 7–13.Google Scholar
  7. 7.
    Skvortsova, V.I. and Evzel’man, M.A., Ishemicheskii insul’t (The Ischemic Stroke), Orel: Media Sfera, 2006.Google Scholar
  8. 8.
    Suslina, Z.A., Ocherki agnionevrologii (Essays on Angioneurology), Moscow: Atmosfera, 2005.Google Scholar
  9. 9.
    Suslina, Z.A., Piradov, M.A., and Domashenko, M.A., Stroke: the review of the problem (15 years later), Zh. Nevrol. Psikhiatr., 2014, vol. 114, no. 11, pp. 5–13.Google Scholar
  10. 10.
    Suslina, Z.A., Tanyashyan, M.M., and Ionova, V.G., Ishemicheskii insul’t (The Ischemic Stroke), Moscow: Meditsinskaya Kniga, 2005.Google Scholar
  11. 11.
    Troshin, V.D., Gustov, A.V., and Troshin, O.V., Ostrye narusheniya mozgovogo krovoobrashcheniya (Acute Dysfunctions of Brain Blood Circulation), Nizhny Novgorod: Novgorod. Gos. Med. Akad., 2000.Google Scholar
  12. 12.
    Fonyakin, A.V., Modern concept of cardioneurology, Ann. Klin. Eksp. Nevrol., 2007, vol. 1, no. 3, pp. 45–48.Google Scholar
  13. 13.
    Adams, H.P., Bendixen, B.H., Kappelle, L.J., et al., Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST: Trial of Org 10172 in Acute Stroke Treatment, Stroke, 1993, vol. 24, no. 1, pp. 35–41.CrossRefPubMedGoogle Scholar
  14. 14.
    Fisher, C., Lacunar strokes and infarcts: a review, Neurology, 1982, vol. 32, no. 8, pp. 871–876.CrossRefPubMedGoogle Scholar
  15. 15.
    Iso, H., Sato, S., Kitamura, A., et al., The risk of ischemic heart disease and stroke among Japanese men and women, Stroke, 2007, vol. 38, pp. 1744–1751.CrossRefPubMedGoogle Scholar
  16. 16.
    Kurl, S., Laukkanen, J.A., Niskanen, L., et al., Metabolic syndrome and the risk in middle-aged men, Stroke, 2006, vol. 37, no. 3, pp. 806–811.CrossRefPubMedGoogle Scholar
  17. 17.
    TOAST Investigators, Low molecular weight heparinoid, ORG 10172 (Danaparoid), and outcome after acute ischemic stroke, JAMA, J. Am. Med. Assoc., 1998, no. 279, pp. 1265–1272.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • V. S. Myakotnykh
    • 1
  • E. Y. Kravtsova
    • 2
  • G. A. Martynova
    • 2
  • R. V. Soloviev
    • 1
  • D. A. Berezina
    • 1
  • T. A. Borovkova
    • 1
  • K. V. Myakotnykh
    • 1
  1. 1.Ural State Medical UniversityYekaterinburgRussia
  2. 2.Wagner Perm State Medical UniversityPermRussia

Personalised recommendations