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Influence of environment on aging of living systems: A mathematical model

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Abstract

A mathematical model simulating the influence of environment (ENV) on aging of living systems is proposed. The model is based on the concept of continuous adaptation of a biological system (BS) to ENV from the moment of its birth. The adaptation rate as the rate of risk of destruction accumulation is regarded as a competition between two concurrent processes—BS destruction and recombination of damages defined by kinetics of autocatalytic chemical reactions. The effect of ENV is taken into account by model parameters, which in general are time-dependent. The model reflects the rules of thermodynamics and gerontology as well as the typical results of medical experiments.

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Correspondence to A. A. Viktorov.

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Original Russian Text © A.A. Viktorov, V.A. Kholodnov, V.D. Gladkikh, A.V. Alekhnovich, 2013, published in Uspekhi Gerontologii, 2013, Vol. 26, No. 1, pp. 52–57.

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Viktorov, A.A., Kholodnov, V.A., Gladkikh, V.D. et al. Influence of environment on aging of living systems: A mathematical model. Adv Gerontol 3, 255–260 (2013). https://doi.org/10.1134/S2079057013040103

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