Advances in Gerontology

, Volume 2, Issue 4, pp 319–322 | Cite as

Description of the immune system of residents of the Russian Far East during physiological aging

  • T. A. Gvozdenko
  • O. Yu. Kytikova
  • T. I. Vitkina
  • P. V. Borshchyov


Basic parameters of the immune status of relatively healthy people of different ages that live in the monsoon climate in the southern part of the Russian Far East have been considered. This data analysis has shown that the development of an immunodepressive condition in combination with increasing amounts of CD 16, CD 25, and HLA-DR is age-dependent and progresses together with aging. The aggressiveness of climatic, geographical, and anthropogenic factors has a deep damaging impact, which results in the degree of manifestation of functional immune disorders among elderly people, older adults, and long-lived people.


immune system physiological aging 


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Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • T. A. Gvozdenko
    • 1
  • O. Yu. Kytikova
    • 1
  • T. I. Vitkina
    • 1
  • P. V. Borshchyov
    • 1
  1. 1.Research and Development Institute of Medical Climatology and Rehabilitation Treatment, Far East Research Center of Physiology and Pathology of Respiration, Siberian BranchRussian Academy of Medical SciencesVladivostokRussia

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