Abstract
Tests of the commercial oxygenators and their prototypes revealed different kinds of defects. These include thrombosis, hemolysis and the occlusion of membrane channels with plasma leukocytes, shunting of the venous blood stream between membrane capillaries or at the wall of the oxygenator. In order to prevent the above-mentioned adverse effects it is necessary to consider and optimize all the physical and chemical processes in the device at the design stage. These include hydrodynamics, masstransfer and chemical (hemoglobin-oxygen saturation) processes. The article considers the method for hydrodynamic mathematical modeling of the blood flow in a membrane oxygenator. The verification of numerical data is also performed. For the verification process a hydrodynamic test bench designed in-house was used. The test data and those of comparative analysis show satisfactory results, which proves that the suggested model can be used for analyzing various aspects of the device operation.
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Original Russian Text © D.O. Yasyukevich, 2008, published in Matematicheskoe Modelirovanie, 2008, Vol. 20, No. 3, pp. 9–16.
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Yasyukevich, D.O. Hydrodynamic processes in medical devices for blood oxygenation. Math Models Comput Simul 1, 296–301 (2009). https://doi.org/10.1134/S2070048209020124
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DOI: https://doi.org/10.1134/S2070048209020124