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Chemical composition and biological activity of triterpenes and steroids of chaga mushroom

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Abstract

Data on the chemical composition of triterpenic and steroid compounds, isolated from the chaga mushroom grown in natural environment or in a synthetic culture have been summarized. Special attention has been paid to the biological activity of chaga mushroom extracts and these particular compounds against various cancer cell lines in vitro and in vivo. This analysis has demonstrated some common features in inhibition of growth of various cell lines by chaga mushroom components. In this context, the most active are triterpene compounds containing OH group at C-22 and a side chain unsaturated bond.

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Authors and Affiliations

  1. Kazan State Technological University, ul. K. Marksa 68, Kazan, 420015, Russia

    S. A. Nikitina, V. R. Habibrakhmanova & M. A. Sysoeva

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  1. S. A. Nikitina
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  2. V. R. Habibrakhmanova
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  3. M. A. Sysoeva
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Original Russian Text © S.A. Nikitina, V.R. Habibrakhmanova, M.A. Sysoeva, 2016, published in Biomeditsinskaya Khimiya.

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Nikitina, S.A., Habibrakhmanova, V.R. & Sysoeva, M.A. Chemical composition and biological activity of triterpenes and steroids of chaga mushroom. Biochem. Moscow Suppl. Ser. B 10, 63–69 (2016). https://doi.org/10.1134/S1990750816010108

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