Electrochemical sensor systems based on one-dimensional (1D) nanostructures for analysis of bioaffinity interactions

  • V. V. Shumyantseva
  • T. V. Bulko
  • E. V. Suprun
  • A. I. Archakov


Modification of screen printed graphite electrodes (SPE) with gold nanoparticles (AuNPs) decorated Pb nanowires (PbNWs) enhances such analytical characteristics of the sensor as effective surface area, electrocatalytic properties and kinetics of heterogeneous electron transfer. The reason for such improvement may be associated with the synergistic effect of AuNPs and PbNWs. Nanowires ensembles on the electrode surface were employed for the detection of cardiac myoglobin in human blood, cytochrome P450 2B4, cytochrome c. Composite materials based on nanoparticles with different dimensions (three dimensional (3D) gold nanoparticles and one dimensional (1D) Pb nanowires) create a platform for electrochemical analysis of proteins with low detection limits.


Pb nanowires gold nanoparticles synergism nanowires ensembles on electrode 


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Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • V. V. Shumyantseva
    • 1
  • T. V. Bulko
    • 1
  • E. V. Suprun
    • 1
  • A. I. Archakov
    • 1
  1. 1.Institute of Biomedical ChemistryRussian Academy of Medical SciencesMoscowRussia

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