Abstract
Electrostatic interaction of plastocyanin and cytochrome f in the process of protein–protein complex formation was investigated by computer simulation methods. It was shown that long-range electrostatic interaction promotes energetically favorable mutual orientation of protein molecules at distances between their cofactors shorter than 5 nm. At distances shorter than 3 nm, these electrostatic interactions lead to a significantly detectable increase in the rate of convergence of the cofactors.
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Original Russian Text © I.B. Kovalenko, S.S. Khrushchev, V.A. Fedorov, G.Yu. Riznichenko, A.B. Rubin, 2016, published in Doklady Akademii Nauk, 2016, Vol. 468, No. 2, pp. 220–224.
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Kovalenko, I.B., Khrushchev, S.S., Fedorov, V.A. et al. The role of electrostatic interactions in the process of diffusional encounter and docking of electron transport proteins. Dokl Biochem Biophys 468, 183–186 (2016). https://doi.org/10.1134/S1607672916030066
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DOI: https://doi.org/10.1134/S1607672916030066