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Doklady Biochemistry and Biophysics

, Volume 468, Issue 1, pp 183–186 | Cite as

The role of electrostatic interactions in the process of diffusional encounter and docking of electron transport proteins

  • I. B. Kovalenko
  • S. S. Khrushchev
  • V. A. Fedorov
  • G. Yu. Riznichenko
  • A. B. Rubin
Biochemistry, Biophysics and Molecular Biology
  • 42 Downloads

Abstract

Electrostatic interaction of plastocyanin and cytochrome f in the process of protein–protein complex formation was investigated by computer simulation methods. It was shown that long-range electrostatic interaction promotes energetically favorable mutual orientation of protein molecules at distances between their cofactors shorter than 5 nm. At distances shorter than 3 nm, these electrostatic interactions lead to a significantly detectable increase in the rate of convergence of the cofactors.

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • I. B. Kovalenko
    • 1
  • S. S. Khrushchev
    • 1
  • V. A. Fedorov
    • 1
  • G. Yu. Riznichenko
    • 1
  • A. B. Rubin
    • 1
  1. 1.Biological FacultyMoscow State UniversityMoscowRussia

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