Advertisement

Doklady Biochemistry and Biophysics

, Volume 466, Issue 1, pp 23–27 | Cite as

Genomic and proteomic profiles of Acholeplasma laidlawii strains differing in sensitivity to ciprofloxacin

  • E. S. Medvedeva
  • M. N. Davydova
  • A. A. Mouzykantov
  • N. B. Baranova
  • T. Yu. Grigoreva
  • M. N. Siniagina
  • E. A. Boulygina
  • O. A. Chernova
  • V. M. Chernov
Biochemistry, Biophysics and Molecular Biology

Abstract

As a result of comparative analysis of complete genomes as well as cell and vesicular proteomes of A. laidlawii strains differing in sensitivity to ciprofloxacin, it was first shown that the mycoplasma resistance to the antibiotic is associated with the reorganization of genomic and proteomic profiles, which concerns many genes and proteins involved in fundamental cellular processes and realization of bacterial virulence.

Keywords

Proteomic Profile Sparfloxacin DOKLADY Biochemistry Extracellular Vesicle ptsA 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Chernov, V.M., Chernova, O.A., Sanches-Vega, Kh.T., et al., Acta Naturae, 2014, vol. 6, pp. 43–54.Google Scholar
  2. 2.
    Mollicutes: Molecular Biology and Pathogenesis, Browning, G.F. and Citti, C., Eds., Caister Acad. Press, 2014.Google Scholar
  3. 3.
    Wright, G.D., Expert. Opin. Drug. Discov., 2010, vol. 5, pp. 779–788.CrossRefPubMedGoogle Scholar
  4. 4.
    Peleg, A.Y., Miyakis, S., Ward, D.V., et al., PLoS One, 2012, vol. 7, p. e28316.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Liu, F., Zhu, Y., Yi, Y., et al., BMC Genomics, 2014, vol. 15, p. 1163.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Chernov, V.M., Mouzykantov, A.A., Baranova, N.B., et al., J. Proteomics, 2014, vol. 110, pp. 117–128.CrossRefPubMedGoogle Scholar
  7. 7.
    Lazarev, V.N., Levitskii, S.A., Basovskii, Y.I., et al., J. Bacteriol., 2011, vol. 193, pp. 4943–4953.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Liu, W., Xiao, S., Li, M., et al., BMC Genomics, 2013, vol. 14, p. 80.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Han, J., Sahin, O., Barton, Y.W., et al., PLoS Pathog., 2008, vol. 4, no. 6, p. e1000083.CrossRefPubMedPubMedCentralGoogle Scholar
  10. 10.
    Lu, J., Vlamis-Gardikas, A., Kandasamy, K., et al., FASEB J., 2013, vol. 27, pp. 1394–1403.CrossRefPubMedGoogle Scholar
  11. 11.
    Park, A.J., Surette, M.D., and Khursigara, C.M., Front. Microbiol., 2014, vol. 5, p. 464.CrossRefPubMedPubMedCentralGoogle Scholar
  12. 12.
    Garneau, J.E., Tremblay, D.M., and Moineau, S., Virology, 2008, vol. 373, pp. 298–309.CrossRefPubMedGoogle Scholar
  13. 13.
    Charpentier, X., Kay, E., Schneider, D., et al., J. Bacteriol., 2011, vol. 193, pp. 1114–1121.CrossRefPubMedPubMedCentralGoogle Scholar
  14. 14.
    Slager, J., Kjos, M., Attaiech, L., et al., Cell, 2014, vol. 157, pp. 395–406.CrossRefPubMedGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • E. S. Medvedeva
    • 1
    • 2
  • M. N. Davydova
    • 1
  • A. A. Mouzykantov
    • 1
    • 2
  • N. B. Baranova
    • 1
    • 2
  • T. Yu. Grigoreva
    • 1
  • M. N. Siniagina
    • 2
  • E. A. Boulygina
    • 2
  • O. A. Chernova
    • 1
    • 2
  • V. M. Chernov
    • 1
    • 2
  1. 1.Kazan Institute of Biochemistry and Biophysics, Kazan Scientific CenterRussian Academy of SciencesKazan TatarstanRussia
  2. 2.Kazan (Volga Region) Federal UniversityKazan TatarstanRussia

Personalised recommendations