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Macroporous polymer materials: Synthesis of a new functional copolymer and its use for biological microanalysis

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Abstract

Macroporous materials based on a new reactive copolymer of 2-cyanoethyl methacrylate, 2-hydroxyethyl methacrylate, and ethylene glycol dimethacrylate have been prepared via photo-induced free-radical polymerization in the presence of porogeneous solvents. The effect of the composition of mixed porogenes on the porous structure of the resulting solid copolymers has been studied. A number of synthesis parameters have been optimized, namely, the concentration of initiator and the time of polymerization. As exemplified by a model biologically complementary (bioaffine) pair, the created polymer material shows promise for design of bioanalytical panels (microbiochips).

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, Bol’shoi pr. 31, St. Petersburg, 199004, Russia

    E. G. Vlakh, E. F. Maksimova, V. D. Krasikov & T. B. Tennikova

Authors
  1. E. G. Vlakh
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  2. E. F. Maksimova
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  3. V. D. Krasikov
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  4. T. B. Tennikova
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Corresponding author

Correspondence to T. B. Tennikova.

Additional information

Original Russian Text © E.G. Vlakh, E.F. Maksimova, V.D. Krasikov, T.B. Tennikova, 2009, published in Vysokomolekulyarnye Soedineniya, Ser. B, 2009, Vol. 51, No. 9, pp. 1677–1685.

This work was supported by the Russian Foundation for Basic Research (project no. 08-08-00876-a) and the Russian Science Support Foundation (2008).

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Vlakh, E.G., Maksimova, E.F., Krasikov, V.D. et al. Macroporous polymer materials: Synthesis of a new functional copolymer and its use for biological microanalysis. Polym. Sci. Ser. B 51, 327 (2009). https://doi.org/10.1134/S1560090409090024

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  • DOI: https://doi.org/10.1134/S1560090409090024

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