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A Modified Synthesis of 6-Aryl-3-(6-R-pyridin-2-yl)-1,2,4-triazines

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Abstract

A practical procedure has been proposed for the synthesis of 6-aryl-3-(pyridin-2-yl)-1,2,4-triazines containing various functional groups in the α-position of the pyridine ring by direct heterocyclization of isonitrosoacetophenone hydrazones with 6-substituted pyridine-2-carbaldehydes.

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Authors and Affiliations

  1. Ural Federal University, ul. Mira 19, Yekaterinburg, 620002, Russia

    O. V. Shabunina, E. S. Starnovskaya, Ya. K. Shtaits, D. S. Kopchuk, I. S. Kovalev, G. V. Zyryanov, V. L. Rusinov & O. N. Chupakhin

  2. Postovskii Institute of Organic Synthesis, Ural Branch, Russian Academy of Sciences, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990, Russia

    D. S. Kopchuk, G. V. Zyryanov, V. L. Rusinov & O. N. Chupakhin

Authors
  1. O. V. Shabunina
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  2. E. S. Starnovskaya
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  3. Ya. K. Shtaits
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  4. D. S. Kopchuk
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  5. I. S. Kovalev
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  6. G. V. Zyryanov
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  7. V. L. Rusinov
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  8. O. N. Chupakhin
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Corresponding author

Correspondence to G. V. Zyryanov.

Additional information

Original Russian Text © O.V. Shabunina, E.S. Starnovskaya, Ya.K. Shtaits, D.S. Kopchuk, I.S. Kovalev, G.V. Zyryanov, V.L. Rusinov, O.N. Chupakhin, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 10, pp. 1561–1563.

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Shabunina, O.V., Starnovskaya, E.S., Shtaits, Y.K. et al. A Modified Synthesis of 6-Aryl-3-(6-R-pyridin-2-yl)-1,2,4-triazines. Russ J Org Chem 54, 1576–1578 (2018). https://doi.org/10.1134/S107042801810024X

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  • DOI: https://doi.org/10.1134/S107042801810024X

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