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Three-Component Stereoselective Synthesis of (1R,2S)-1-Aryl-2-{[prop-2-yn(en)yloxy]methyl}spiro[2,4]hepta-4,7-diones

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Abstract

Three-component reaction involving cyclopentane-1,3-dione, substituted benzaldehydes, and chloromethyl propyn(en)yl ethers results in a stereoselective formation of trans-1-aryl-2-{[prop-2-(yn)enyloxy]-methyl}spiro[2,4]hepta-4,7-diones in satisfactory yields.

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Correspondence to G. M. Talybov.

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Original Russian Text © G.M. Talybov, 2018, published in Zhurnal Organicheskoi Khimii, 2018, Vol. 54, No. 8, pp. 1242–1245.

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Talybov, G.M. Three-Component Stereoselective Synthesis of (1R,2S)-1-Aryl-2-{[prop-2-yn(en)yloxy]methyl}spiro[2,4]hepta-4,7-diones. Russ J Org Chem 54, 1256–1259 (2018). https://doi.org/10.1134/S1070428018080225

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  • DOI: https://doi.org/10.1134/S1070428018080225

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