Russian Journal of Organic Chemistry

, Volume 52, Issue 11, pp 1610–1615 | Cite as

Dehydrogenation of 1-aryl(hetaryl)-1,2,3,4-tetrahydro-9H-β-carboline-3-carboxylic acids and their esters with dimethyl sulfoxide

  • M. G. Abramyants
  • D. A. Lomov
  • T. I. Zavyazkina
Article
  • 71 Downloads

Abstract

Oxidative dehydrogenation of 1-aryl(hetaryl)-1,2,3,4-tetrahydro-9Н-β-carboline-3-carboxylic acids derivatives with dimethyl sulfoxide leads to the formation of 1-aryl(hetaryl)-9Н-β-carbolines. Simultaneously with the dehydrogenation decarboxylation occurs. At the oxidation with dimethyl sulfoxide of methyl 1-aryl (hetaryl)-1,2,3,4-tetrahydro-9Н-β-carboline-3-carboxylicates methyl 1-aryl(hetaryl)-9Н-β-carboline-3-carboxylates formed whose hydrolysis afforded the corresponding 1-aryl(hetaryl)-9Н-β-carboline-3-carboxylic acids.

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • M. G. Abramyants
    • 1
  • D. A. Lomov
    • 1
  • T. I. Zavyazkina
    • 1
  1. 1.Litvinenko Institute of Physical Organic and Coal ChemistryDonetskUkraine

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