Chlorination and decarboxylation of (heptafluoronaphthalen-2-yl)acetic acid. Synthesis of 2-(dichloromethyl)- and 2-(difluoromethyl)heptafluoronaphthalenes
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Decarboxylation of (heptafluoronaphthalen-2-yl)acetic acid in DMF in the presence of NaHCO3 gave 2-methylheptafluoronaphthalene, and treatment with PCl5 on heating afforded dichloro(heptafluoronaphthalen-2-yl)acetic acid. Decarboxylation of the latter in DMF led to the formation of 2-(dichloromethyl)-heptafluoronaphthalene which was converted to 2-(difluoromethyl)heptafluoronaphthalene by heating with cesium fluoride.
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- 1.Vlasov, V.M. and Yakobson, G.G., J. Org. Chem. USSR, 1976, vol. 12, p. 2345.Google Scholar
- 6.Klimenko, L.S., Karpov, V.M., Platonov, V.E., and Yakobson, G.G., J. Org. Chem. USSR, 1979, vol. 15, p. 130.Google Scholar
- 7.Gething, B., Patrick, C.R., Smith, B.J.K., and Tatlow, J.C., J. Chem. Soc., 1962, p. 190.Google Scholar
- 8.Shteingarts, V.D., Osina, O.I., Kostina, N.G., and Yakobson, G.G., Zh. Org. Khim., 1970, vol. 6, p. 833.Google Scholar