Abstract
Reactions of 4,6-dinitro-5,7-dichlorobenzofuroxane with substituted pyrimidines in aqueous DMSO proceed through an intermediate formation of 5-hydroxy-4,6-dinitro-7-chlorobenzofuroxane owing to the hydrolysis of one of the chlorine atoms with the subsequent formation of pyrimidine salts exhibiting a high biologic action.
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Original Russian Text © I.V. Galkina, L.M. Yusupova, A.T. Gubaidullin, V.I. Galkin, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 5, pp. 744–749.
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Galkina, I.V., Yusupova, L.M., Gubaidullin, A.T. et al. Synthesis, structure, and biologic activity of products of reactions between dinitrodichlorobenzofuroxane and aminopyrimidines in aqueous dimethyl sulfoxide. Russ J Org Chem 52, 734–739 (2016). https://doi.org/10.1134/S1070428016050201
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DOI: https://doi.org/10.1134/S1070428016050201