Russian Journal of Organic Chemistry

, Volume 52, Issue 5, pp 734–739 | Cite as

Synthesis, structure, and biologic activity of products of reactions between dinitrodichlorobenzofuroxane and aminopyrimidines in aqueous dimethyl sulfoxide

  • I. V. Galkina
  • L. M. Yusupova
  • A. T. Gubaidullin
  • V. I. Galkin


Reactions of 4,6-dinitro-5,7-dichlorobenzofuroxane with substituted pyrimidines in aqueous DMSO proceed through an intermediate formation of 5-hydroxy-4,6-dinitro-7-chlorobenzofuroxane owing to the hydrolysis of one of the chlorine atoms with the subsequent formation of pyrimidine salts exhibiting a high biologic action.


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • I. V. Galkina
    • 1
  • L. M. Yusupova
    • 2
  • A. T. Gubaidullin
    • 3
  • V. I. Galkin
    • 1
  1. 1.Kazan (Volga region) Federal UniversityKazanRussia
  2. 2.Kazan National Research Technologic UniversityKazanRussia
  3. 3.Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific CenterRussian Academy of SciencesKazanRussia

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