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N-(4-methoxy-3-nitrobenzyl) derivatives of some nitrogen-containing heterocycles

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Abstract

A number of nitrogen heterocycles reacted with 4-methoxy-3-nitrobenzyl chloride in dimethyl-formamide in the presence of potassium carbonate to give the corresponding N-(4-methoxy-3-nitrobenzyl) derivatives. The reaction of 5-fluoro-1,3-bis(4-methoxy-3-nitrobenzyl)pyrimidine-2,4(1H,3H)-dione with aqueous methylamine afforded N,N′-bis(4-methylamino-3-nitrobenzyl)urea, whereas analogous reaction with 1-(4-methoxy-3-nitrobenzyl)-2-(methylsulfanyl)-1H-benzimidazole resulted in substitution of the methoxy group by methylamino.

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References

  1. Shmidt, M.S., Reverdito, A.M., Kremenchuzky, L., Perillo, I.A., and Blanco, M.M., Molecules, 2008, vol. 13, p. 831.

    Article  CAS  Google Scholar 

  2. Walia, R., Hedaitullah, Md., Naaz, S.F., Iqbal, K., and Lamba, H.S., Int. J. Res. Pharm. Chem., 2011, vol. 1, p. 565.

    CAS  Google Scholar 

  3. Arutyunyan, A.A., Mamyan, S.S., Stepanyan, G.M., and Paronikyan, R.V., Pharm. Chem. J., 2013, vol. 47, no. 6, p. 303.

    Article  CAS  Google Scholar 

  4. Arutyunyan, A.A., Khim. Zh. Arm., 2012, vol. 6, no. 3, p. 317.

    Google Scholar 

  5. Melik-Ogandzhanyan, R.G., Khachatryan, V.E., Avoyan, R.S., Okhikyan, V.M., and Papoyan, S.A., Khimioter. Opukholei SSSR, 1979, no. 27, p. 108.

    Google Scholar 

  6. Harutyunyan, A.A., Russ. J. Org. Chem., 2014, vol. 50, p. 94.

    Article  CAS  Google Scholar 

  7. Beilsteins Handb. Org. Chem., H, vol. 6, p. 218.

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Authors and Affiliations

  1. Mndzhoyan Institute of Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, Yerevan, 0014, Armenia

    A. A. Harutyunyan

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  1. A. A. Harutyunyan
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Correspondence to A. A. Harutyunyan.

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Original Russian Text © A.A. Harutyunyan, 2016, published in Zhurnal Organicheskoi Khimii, 2016, Vol. 52, No. 1, pp. 83–86.

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Harutyunyan, A.A. N-(4-methoxy-3-nitrobenzyl) derivatives of some nitrogen-containing heterocycles. Russ J Org Chem 52, 76–79 (2016). https://doi.org/10.1134/S1070428016010140

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  • DOI: https://doi.org/10.1134/S1070428016010140

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