Russian Journal of Organic Chemistry

, Volume 51, Issue 11, pp 1633–1641 | Cite as

C- and O-alkylation of ecdysteroids in lithium-ammonia solution

  • I. V. Galyautdinov
  • Z. R. Khairullina
  • O. S. Mozgovoi
  • L. M. Khalilov
  • Z. S. Muslimov
  • V. N. Odinokov
Article
  • 38 Downloads

Abstract

Reactions of ecdysteroids with alkyl halides in lithium-ammonia solution stereospecifically led to the formation of 7α-alkylated 14-deoxy-Δ8(14)-ecdysteroids. In the presence in the initial compound of free secondary hydroxy groups in the positions 2, 3, or 22 in some cases a side process of О-alkylation as well occurred.

Keywords

MeOH Methyl Iodide Ecdysone HSQC Spectrum Hydroxyecdysone 

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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • I. V. Galyautdinov
    • 1
  • Z. R. Khairullina
    • 1
  • O. S. Mozgovoi
    • 1
  • L. M. Khalilov
    • 1
  • Z. S. Muslimov
    • 1
  • V. N. Odinokov
    • 1
  1. 1.Institute of Petrochemistry and CatalysisRussian Academy of SciencesUfaBashkortostanRussia

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