Russian Journal of Organic Chemistry

, Volume 51, Issue 6, pp 864–868 | Cite as

Multicomponent synthesis of 2-(alkylsulfanyl)-4-[furan-2-yl-(or thiophen-2-yl)]-5,6,7,8-tetrahydroquinoline-3-carbonitriles

  • V. D. Dyachenko
  • V. N. Nesterov
  • S. V. Dyachenko
  • A. V. Chernykh


Substituted 2-(alkylsulfanyl)-4-[furan-2-yl(or thiophen-2-yl)]-5,6,7,8-tetrahydroquinoline-3-carbonitriles were synthesized by condensation of furfural or thiophene-2-carbaldehyde with 2-cyanoethanethioamide, 1-(cyclohex-1-en-1-yl)pyrrolidine, and alkyl halides. The structure of methyl 2-{[3-cyano-4-(thiophen-2-yl)-5,6,7,8-tetrahydroquinolin-2-yl]sulfanyl}acetate was determined by X-ray analysis.


Yellow Powder Alkyl Halide Sulfanyl Methylsulfanyl Fluoroacetic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • V. D. Dyachenko
    • 1
  • V. N. Nesterov
    • 2
  • S. V. Dyachenko
    • 1
  • A. V. Chernykh
    • 3
  1. 1.Taras Shevchenko Lugansk National UniversityLuganskUkraine
  2. 2.University of North TexasDentonUSA
  3. 3.Institute of Organic ChemistryNational Academy of Sciences of UkraineKievUkraine

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