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Synthesis of functionalized pyrazoles from pyrazolecarbaldehydes and amino alcohols

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Abstract

1,3,5-Trialkyl-1H-pyrazole-4-carbaldehydes reacted with amino alcohols at ambient temperature in the absence of a catalyst to give the corresponding Schiff bases which failed to undergo cyclization to 2-(pyrazol-4-yl)-1,3-oxazolidines on heating in the presence of dehydrating agents.

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Authors and Affiliations

  1. Favorskii Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, ul. Favorskogo 1, Irkutsk, 664033, Russia

    L. K. Papernaya, A. A. Shatrova, A. I. Albanov & G. G. Levkovskaya

Authors
  1. L. K. Papernaya
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  2. A. A. Shatrova
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  3. A. I. Albanov
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  4. G. G. Levkovskaya
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Corresponding author

Correspondence to L. K. Papernaya.

Additional information

Original Russian Text © L.K. Papernaya, A.A. Shatrova, A.I. Albanov, G.G. Levkovskaya, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 4, pp. 539–542.

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Papernaya, L.K., Shatrova, A.A., Albanov, A.I. et al. Synthesis of functionalized pyrazoles from pyrazolecarbaldehydes and amino alcohols. Russ J Org Chem 51, 522–525 (2015). https://doi.org/10.1134/S1070428015040107

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  • DOI: https://doi.org/10.1134/S1070428015040107

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