Russian Journal of Organic Chemistry

, Volume 51, Issue 1, pp 101–109 | Cite as

Synthesis of N-aryl benzamides containing pharmacophoric tyrosine kinase inhibitor fragments

  • E. V. Koroleva
  • Zh. V. Ignatovich
  • K. N. Gusak
  • A. L. Ermolinskaya
  • Yu. V. Sinyutich
Article

Abstract

New N-aryl 4-(arylaminomethyl)benzamides containing pharmacophoric heterocyclic fragments have been synthesized from 2-arylaminopyrimidine, 1-methylpiperazine, and morpholine derivatives and substituted benzoic acids.

Keywords

Piperazine Benzamide Raney Nickel Amino Amide Benzotriazolyl 

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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • E. V. Koroleva
    • 1
  • Zh. V. Ignatovich
    • 1
  • K. N. Gusak
    • 1
  • A. L. Ermolinskaya
    • 1
  • Yu. V. Sinyutich
    • 1
  1. 1.Institute of New Materials ChemistryNational Academy of Sciences of BelarusMinskBelarus

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