Russian Journal of Organic Chemistry

, Volume 50, Issue 5, pp 685–690 | Cite as

5-Amino-N-(2,2-dialkoxyethyl)pyrazole-4-carboxamides in the synthesis of 7-sulfanyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-e][1,4]diazepin-4-ones



5-Amino-N-(2,2-dialkoxyethyl)pyrazole-4-carboxamides obtained by hydrolytic cleavage of 5-(2,2-diethoxyethyl)pyrazolo[3,4-d]pyrimidin-4-ones or by condensation of 3-(dimethylamino)-N-(2,2-dimethoxyethyl)-2-cyanoacrylamides with alkylhydrazines in formic acid react with benzylthiol or thiophenols to afford 7-benzyl(aryl)sulfanyl-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-e][1,4]diazepin-4-ones.


Hydrazine Hydrate Sulfanyl Hydrolytic Cleavage Ethyl Cyanoacetate Diazepine Ring 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Pleiades Publishing, Ltd. 2014

Authors and Affiliations

  1. 1.Institute of Organic ChemistryNational Academy of Sciences of UkraineKievUkraine

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