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Russian Journal of Organic Chemistry

, Volume 50, Issue 1, pp 21–24 | Cite as

Transamination of α-amino nitriles

  • Yu. V. Popov
  • V. M. Mokhov
  • N. A. Tankabekyan
Article

Abstract

α-Amino nitriles containing a primary amino group undergo transamination with aliphatic and aromatic amines under mild conditions with high yields. A probable reaction mechanism involving intermediate elimination of cyanide ion has been proposed.

Keywords

Potassium Carbonate Cyano Group Ketimine Acetone Cyanohydrin Carboxylic Acid Amide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Strecker, A., Ann. Chem. Pharm., 1850, vol. 75, p. 27.CrossRefGoogle Scholar
  2. 2.
    Bucherer, H.T. and Steiner, W., J. Prakt. Chem., 1934, vol. 140, p. 291.Google Scholar
  3. 3.
    Evans, D.A., Truesdale, L.K., and Carroll, G.L., J. Chem. Soc., Chem. Commun., 1973, p. 55.Google Scholar
  4. 4.
    Bauer, O.W. and Teter, J.W., US Patent no. 2 552 026; Chem. Abstr., 1951, vol. 45, p. 9074.Google Scholar
  5. 5.
    Domkin, V.D. and Kur’yanovich, A.A., Zh. Org. Khim., 1976, vol. 12, p. 908.Google Scholar
  6. 6.
    Brown, T., Shaw, G., and Durant, G.J., J. Chem. Soc., Perkin Trans. 1, 1980, p. 2310.Google Scholar
  7. 7.
    Popov, Yu.V., Mokhov, V.M., Tankabekyan, N.A., and Safronova, O.Yu., Russ. J. Appl. Chem., 2012, vol. 85, p. 1387.CrossRefGoogle Scholar
  8. 8.
    Shakhidayatov, Kh., Zh. Org. Khim., 1973, vol. 9, p. 1373.Google Scholar
  9. 9.
    Shafran, Yu.M., Bakulev, V.A., and Mokrushin, V.S., Usp. Khim., 1989, vol. 58, p. 250.CrossRefGoogle Scholar
  10. 10.
    Freifelder, M. and Hasbrouck, R.B., J. Am. Chem. Soc., 1960, vol. 82, p. 696.CrossRefGoogle Scholar
  11. 11.
    Popov, Yu.V., Mokhov, V.M., and Tankabekyan, N.A., Russ. J. Org. Chem., 2013, vol. 49, p. 1135.CrossRefGoogle Scholar
  12. 12.
    Wendelin, W., Kern, W., Zmolnig, I., and Schramm, H., Monatsh. Chem., 1981, vol. 112, p. 1091.CrossRefGoogle Scholar
  13. 13.
    Barreau, M., Chottard, J.-C., Le Peco, J-B., and Mailliet, P., US Patent no. 5 225 207, 1993.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2014

Authors and Affiliations

  • Yu. V. Popov
    • 1
  • V. M. Mokhov
    • 1
  • N. A. Tankabekyan
    • 1
  1. 1.Volgograd State Technical UniversityVolgogradRussia

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