Russian Journal of Organic Chemistry

, Volume 49, Issue 8, pp 1135–1138 | Cite as

One-stage synthesis of adamantyl-containing α-aminonitriles

  • Yu. V. Popov
  • V. M. Mokhov
  • N. A. Tankabekyan


Reactions of 2-adamantan-2-one, acetone cyanohydrin, and amine lead to the formation of substituted 2-amino-2-cyanoadamantanes. The reaction is of a general character as has been proved by examples on a series of ketones and amines and it proceeds through the formation from the acetone cyanohydrin and amines of 2-amino-2-cyanopropane derivatives reacting further with the carbonyl compounds.


Morpholine Potassium Carbonate Adamantyl Methyl Isobutyl Ketone Rimantadine 
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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • Yu. V. Popov
    • 1
  • V. M. Mokhov
    • 1
  • N. A. Tankabekyan
    • 1
  1. 1.Volgograd State Technical UniversityVolgogradRussia

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