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Russian Journal of Organic Chemistry

, Volume 49, Issue 6, pp 886–889 | Cite as

Derivatives of α,β-dehydro amino acids: VI. Reaction of 4-benzylidene-2-phenyl-1,3-oxazol-5(4H)-one with piperidin-2-ylmethanamine

  • V. O. Topuzyan
  • A. R. Manvelyan
  • V. V. Grigoryan
  • R. A. Tamazyan
  • A. G. Aivazyan
Review

Abstract

4-Benzylidene-2-phenyl-1,3-oxazol-5(4H)-one reacts with piperidin-2-ylmethanamine to give N-{(Z)-3-oxo-3-[(piperidin-2-ylmethyl)amino]-1-phenylprop-1-en-2-yl}benzamide, N-(4-benzyl-3-oxooctahydro-2N-pyrido[1,2-a]pyrazin-4-yl)benzamide, or/and (Z)-4-benzylidenehexahydro-2H-pyrido[1,2-a]pyrazin-3(2H)-one, depending on the solvent, temperature, and reaction time. The latter product is formed via three-step tandem process.

Keywords

Ethyl Acetate Benzamide Compound Versus Oxazolone Amino Amide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Topuzyan, V.O., Kazandzhyan, M.M., Tamazyan, R.A., and Aivazyan, A.G., Russ. J. Org. Chem., 2009, vol. 45, p. 215.CrossRefGoogle Scholar
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    Topuzyan, V.O. and Khachvankyaan, G.Yu., Khim. Zh. Arm., 1996, vol. 49, p. 138.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • V. O. Topuzyan
    • 1
  • A. R. Manvelyan
    • 1
  • V. V. Grigoryan
    • 1
  • R. A. Tamazyan
    • 1
  • A. G. Aivazyan
    • 1
  1. 1.Mndzhoyan Institute of Fine Organic Chemistry, Scientific-Technological Center of Organic and Pharmaceutical ChemistryNational Academy of Sciences of ArmeniaYerevanArmenia

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