Russian Journal of Organic Chemistry

, Volume 49, Issue 3, pp 356–359 | Cite as

Synthesis of secondary propargyl alcohols from aromatic and heteroaromatic aldehydes and acetylene in the system KOH-H2O-DMSO

  • L. N. Sobenina
  • D. N. Tomilin
  • O. V. Petrova
  • A. I. Mikhaleva
  • B. A. Trofimov
Article

Abstract

Ethynylation of aromatic and heteroaromatic aldehydes with acetylene under atmospheric pressure in the catalytic system KOH-H2O-DMSO (aldehyde-KOH molar ratio 1 : 2, −5 to −7°C, 3 h) gave secondary propargyl alcohols in 46–67% yield.

Keywords

Acetylene Aliphatic Aldehyde Vinyl Ketone Propargyl Alcohol Alkali Metal Hydroxide 

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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • L. N. Sobenina
    • 1
  • D. N. Tomilin
    • 1
  • O. V. Petrova
    • 1
  • A. I. Mikhaleva
    • 1
  • B. A. Trofimov
    • 1
  1. 1.Favorskii Irkutsk Institute of Chemistry, Siberian BranchRussian Academy of SciencesIrkutskRussia

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