Russian Journal of Organic Chemistry

, Volume 48, Issue 6, pp 799–803 | Cite as

Synthesis of 2-substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids

  • D. A. Rudenko
  • S. N. Shurov
  • M. I. Kodess
  • M. A. Ezhikova
  • A. N. Vasyanin
Article

Abstract

2-Substituted 7,7-dimethyl-5-oxo-5,6,7,8-tetrahydroquinoline-4-carboxylic acids were synthesized by reaction of acyl- and aroylpyruvic acids with 3-amino-5,5-dimethylcyclohex-2-en-1-one. A plausible mechanism of their formation was proposed on the basis of ab initio quantum-chemical calculations.

Keywords

Enamino Ketone Aroylpyruvic Acid HMBC Technique Benzoyl Carbonyl Reaction Coordinate Method 

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Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • D. A. Rudenko
    • 1
  • S. N. Shurov
    • 1
  • M. I. Kodess
    • 2
  • M. A. Ezhikova
    • 2
  • A. N. Vasyanin
    • 1
  1. 1.Perm State National Research UniversityPermRussia
  2. 2.Postovskii Institute of Organic Synthesis, Ural DivisionRussian Academy of SciencesYekaterinburgRussia

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