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Russian Journal of Organic Chemistry

, Volume 48, Issue 3, pp 426–429 | Cite as

Regioselective reaction of 5,6-dialkyl-2-halopyridine-3,4-dicarbonitriles with ammonia

  • V. N. Maksimova
  • O. V. Ershov
  • K. V. Lipin
  • A. V. Eremkin
  • O. E. Nasakin
Article

Abstract

The reaction of 5,6-dialkyl-2-halopyridine-3,4-dicarbonitriles with alcoholic ammonia under elevated pressure gave 5,6-dialkyl-2-aminopyridine-3,4-dicarbonitriles as a result of nucleophilic replacement of the halogen atom by amino group. 6,7-Dialkyl-4-halo-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diimines were formed in analogous reaction at room temperature in the presence of potassium carbonate.

Keywords

Halogen Atom Potassium Carbonate Cyano Group Dicarbonitriles Sodium Hydrogen Carbonate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • V. N. Maksimova
    • 1
  • O. V. Ershov
    • 1
  • K. V. Lipin
    • 1
  • A. V. Eremkin
    • 1
  • O. E. Nasakin
    • 1
  1. 1.I.N. Ul’yanov Chuvash State UniversityCheboksaryRussia

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