Abstract
5-Phenyl(p-tolyl)isoxazole-3-carboxylic acids were synthesized starting from 3-hydroxyiminomethyl-5-phenyl(p-tolyl)isoxazoles, and their reactions with p-hydroxybenzaldehyde, vanillin, isovanillin, o-vanillin, and ethyl vanillin gave the corresponding esters. The latter were brought into condensation with aromatic amines to obtain Schiff bases which were reduced to amines.
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Original Russian Text © V.I. Potkin, R.A. Gadzhily, E.A. Dikusar, S.K. Petkevich, N.A. Zhukovskaya, A.G. Aliev, Sh.F. Nagieva, 2012, published in Zhurnal Organicheskoi Khimii, 2012, Vol. 48, No. 1, pp. 132–141.
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Potkin, V.I., Gadzhily, R.A., Dikusar, E.A. et al. Synthesis of hydroxybenzaldehyde derivatives containing an isoxazole heteroring. Russ J Org Chem 48, 127–136 (2012). https://doi.org/10.1134/S1070428012010216
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DOI: https://doi.org/10.1134/S1070428012010216