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Chemistry of naphthazarin derivatives: XV. Bromination of naphthazarin and its derivatives

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Abstract

Bromination of a number of naphthazarin (5,8-dihydroxy-1,4-naphthoquinone) derivatives having different substituents in the aromatic ring with molecular bromine in carbon tetrachloride was studied. Preparative procedures for the synthesis of 2-bromo-5,8-dihydroxy-7-methoxy-1,4-naphthoquinone, 2-bromo-6,7-dichloro-5,8-dihydroxy-1,4-naphthoquinone, 2-bromo-3,5,8-trihydroxy-1,4-naphthoquinone, and 2-bromo-6,7-dichloro-3,5,8-trihydroxy-1,4-naphthoquinone were developed.

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Authors and Affiliations

  1. Pacific Institute of Bioorganic Chemistry, Far East Division, Russian Academy of Sciences, pr. 100-letiya Vladivostoka 159, Vladivostok, 690022, Russia

    N. D. Pokhilo, A. Ya. Yakubovskaya & V. P. Glazunov

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  1. N. D. Pokhilo
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  2. A. Ya. Yakubovskaya
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  3. V. P. Glazunov
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Correspondence to N. D. Pokhilo.

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Original Russian Text © N.D. Pokhilo, A.Ya. Yakubovskaya, V.P. Glazunov, 2011, published in Zhurnal Organicheskoi Khimii, 2011, Vol. 47, No. 4, pp. 507–512.

For communication XIV, see [1].

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Pokhilo, N.D., Yakubovskaya, A.Y. & Glazunov, V.P. Chemistry of naphthazarin derivatives: XV. Bromination of naphthazarin and its derivatives. Russ J Org Chem 47, 504–509 (2011). https://doi.org/10.1134/S1070428011040063

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  • DOI: https://doi.org/10.1134/S1070428011040063

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