Russian Journal of Organic Chemistry

, Volume 47, Issue 3, pp 371–373 | Cite as

Ionic liquid-phase organic synthesis (IoLiPOS) methodology applied to cross aldol reaction

  • H. Hakkou
  • D. Carrié
  • L. Paquin
  • J. -P. Bazureau


Cross aldol reaction in task-specific ionic liquids was developed. Ionic liquid-phase bound aldehyde reacted with various ketones (acetone, cyclopentanone, and butan-2-one) with l-proline as catalyst to afford various ionic liquid-phase supported aldols in yields ranging from 81 to 99%. Detachment of the aldol in MeOH was realized by transesterification using 15% of MeONa. The structure of intermediates in each step was verified by spectroscopic analysis.


Ionic Liquid Aldol Cyclopentanone Aldol Reaction MeONa 
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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • H. Hakkou
    • 1
  • D. Carrié
    • 1
  • L. Paquin
    • 1
  • J. -P. Bazureau
    • 1
  1. 1.Laboratoire Sciences Chimiques de Rennes, UMR CNRS 6226, Groupe Ingénierie Chimique & Molécules pour le Vivant (ICMV), Bât. 10A, Campus de BeaulieuUniversité de Rennes 1RENNES CedexFrance

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