Russian Journal of Organic Chemistry

, Volume 46, Issue 3, pp 368–371 | Cite as

Synthesis of substituted methyl 5,5-polymethylene-2,4-dioxotetrahydropyran-3-carboxylates

  • N. F. Kirillov
  • V. S. Melekhin
  • S. N. Shurov
  • A. V. Plotnikov
  • M. I. Vakhrin
  • O. A. Maiorova
Article

Abstract

Dimethyl 2-(1-bromocyclohexylcarbonyl)-, 2-(1-bromocyclopentylcarbonyl)-, and 2-(1-bromocyclobutylcarbonyl)-2-methylmalonates reacted with zinc and aromatic aldehydes to give the corresponding methyl 1-aryl-4-methyl-3,5-dioxo-2-oxaspiro[5.5]undecane-4-, 6-aryl-9-methyl-8,10-dioxo-7-oxaspiro[4.5]-decane-9-, and 5-aryl-8-methyl-7,9-dioxo-6-oxaspiro[3.5]nonane-8-carboxylates.

Keywords

Aromatic Aldehyde Dioxo Cyclohexane Ring Methylmalonate Molecular Bromine 

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References

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Copyright information

© Pleiades Publishing, Ltd. 2010

Authors and Affiliations

  • N. F. Kirillov
    • 1
  • V. S. Melekhin
    • 1
  • S. N. Shurov
    • 1
  • A. V. Plotnikov
    • 1
  • M. I. Vakhrin
    • 1
  • O. A. Maiorova
    • 2
  1. 1.Perm State UniversityPermRussia
  2. 2.Institute of Technical Chemistry, Ural DivisionRussian Academy of SciencesPermRussia

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