Asymmetric oxidation of 4-nitro-6-trifluoromethyl-1,2,3-benzotrithiole

  • T. M. Khomenko
  • D. V. Korchagina
  • K. P. Volcho
  • N. F. Salakhutdinov
Article

Abstract

Both enantiomers of 4-nitro-6-trifluoromethyl-1,2,3-benzotrithiole 1-oxide as analogs of Varacins B and C were synthesized for the first time. The use of the Modena method ensures higher optical purity but lower yields of the chiral sulfoxides, as compared to the Kagan procedure.

Keywords

NaHS Anhydrous Methylene Chloride Cumyl Peroxyacetic Acid High Optical Purity 

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Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • T. M. Khomenko
    • 1
  • D. V. Korchagina
    • 1
  • K. P. Volcho
    • 1
  • N. F. Salakhutdinov
    • 1
  1. 1.Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian DivisionRussian Academy of SciencesNovosibirskRussia

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