Russian Journal of Organic Chemistry

, Volume 45, Issue 5, pp 766–772 | Cite as

Transformations of 5,6,7,8-tetrafluoro-2-ethoxycarbonylchromone under the action of primary amines

  • K. V. Shcherbakov
  • Ya. V. Burgart
  • V. I. Saloutin
Article

Abstract

5,6,7,8-Tetrafluoro-2-ethoxycarbonylchromone in aprotic polar solutions formed by nucleophilic aromatic ipso-substitution 7-alkyl(aryl)amino-5,6,8-trifluorochromones. This transformation in ethanol depended on the reactivity of the acting amine: with stronger nucleophiles, aliphatic amines, an opening of the γ-pyrone ring occurred, with aromatic amines 7-monosubstituted chromones were the main products, and the open-chain esters formed in lesser amount.

Keywords

Methylamine Yellow Powder Chromone Cyclohexylamine Tetrafluorophenyl 

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Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • K. V. Shcherbakov
    • 1
  • Ya. V. Burgart
    • 1
  • V. I. Saloutin
    • 1
  1. 1.Postovsky Institute of Organic Synthesis, Ural DivisionRussian Academy of SciencesYekaterinburgRussia

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