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Synthesis of Schiff bases and oxazolidines from 2-amino-4-phenylthiazole

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Abstract

Reactions of 2-amino-4-phenylthiazole with aromatic aldehydes gave the corresponding Schiff bases which were reduced with sodium tetrahydridoborate to amines. Reactions of the Schiff bases with 2-methyloxirane, 2-chloromethyloxirane, and 2-phenoxymethyloxirane led to the formation of 2,5-disubstituted 3-(4-phenylthiazol-2-yl)oxazolidines.

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References

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Correspondence to S. E. Sadigova.

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Original Russian Text © S.E. Sadigova, A.M. Magerramov, M.A. Allakhverdiev, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 12, pp. 1848–1850.

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Sadigova, S.E., Magerramov, A.M. & Allakhverdiev, M.A. Synthesis of Schiff bases and oxazolidines from 2-amino-4-phenylthiazole. Russ J Org Chem 44, 1821–1823 (2008). https://doi.org/10.1134/S107042800812018X

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  • DOI: https://doi.org/10.1134/S107042800812018X

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