Abstract
A convenient one-step procedure has been developed for the synthesis of fluorine-containing 2-(adamant-l-yl)-1,3-diketones by reaction of fluorinated 1,3-diketones with 1,3-dehydroadamantane. The products can be used as starting compounds for the preparation of new fluorinated adamantyl-containing heterocyclic compounds.
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References
Organofluorine Compounds in Medicinal Chemistry and Biomedical Applications, Filler, R., Kobayashi, Y., and Yagupolskii, L.M., Eds., Amsterdam: Elsevier, 1993.
Walker, S.B., Fluorine Compounds as Agrochemicals, Old Glossop (UK): Fluorochem Ltd., 1990.
Welch, J.T., Tetrahedron, 1987, vol. 43, p. 3123.
Furin, G.G., Ftorsoderzhashchie geterotsiklicheskie soedineniya. Sintez i primenenie (Fluorine-Containing Heterocyclic Compounds. Synthesis and Applications), Moscow: Nauka, 2001.
Morozov, I.S., Petrov, V.I., and Sergeeva, S.A., Farmakologiya adamantanov (Pharmacology of Adamantanes), Volgograd: Volgograd. Med. Akad., 2001.
Pashkevich, K.I., Saloutin, V.I., and Postovskii, I.Ya., Usp. Khim., 1981, vol. 50, p. 325.
No, B.I., Butov, G.M., Mokhov, V.M., and Parshin, G.Yu., Russ. J. Org. Chem., 2003, vol. 39, p. 1668.
No, B.I., Butov, G.M., Mokhov, V.M., and Parshin, G.Yu., Russ. J. Org. Chem., 2002, vol. 38, p. 1377.
Shchapin, I.Yu., Belopushkin, S.I., and Tyurin, D.A., Dokl. Ross. Akad. Nauk, 2000, vol. 372, p. 60.
Stohrer, W.D. and Hoffmann, R., J. Am. Chem. Soc., 1972, vol. 94, p. 779.
Shevelev, S.A., Usp. Khim., 1970, vol. 39, p. 1773.
Katsuyama, I., Ogawa, S., and Yamaguchi, Y., Synthesis, 1997, p. 1321.
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Original Russian Text © G.M. Butov, V.M. Mokhov, G.Yu. Parshin, R.U. Kunaev, S.A. Shevelev, I.L. Dalinger, I.A. Vatsadze, 2008, published in Zhurnal Organicheskoi Khimii, 2008, Vol. 44, No. 8, pp. 1171–1174.
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Butov, G.M., Mokhov, V.M., Parshin, G.Y. et al. Adamantyl-containing fluorinated 1,3-diketones. Russ J Org Chem 44, 1157–1160 (2008). https://doi.org/10.1134/S1070428008080083
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DOI: https://doi.org/10.1134/S1070428008080083