Condensation of diethyl 2,4,6-Trioxoheptanedioate with 2-(Aryliminomethyl)phenols. A new synthesis of chromeno[4,3-b]pyridines

  • V. A. Mamedov
  • A. M. Murtazina
  • L. P. Sysoeva
  • E. V. Mironova
  • Sh. K. Latypov
  • A. A. Balandina
  • S. F. Kadyrova
  • A. T. Gubaidullin
  • I. A. Litvinov
Article

Abstract

Condensation of diethyl 2,4,6-trioxoheptanedioate with 4-methoxy-2-(4-methylphenyliminomethyl)-phenol in acetone gave diethyl 5-hydroxy-9-methoxy-1-(4-methylphenyl)-4-oxo-1,4a,5,10b-tetrahydro-4Hchromeno[ 4,3-b]pyridine-2,5-dicarboxylate as a mixture of diastereoisomers. The major (4aR,5R,10aR)-isomer was isolated as individual substance, and its structure was proved by X-ray analysis.

Keywords

Dicarboxylate Methyl Carbon Atom Iminomethyl Dioate Ester Ethyl Group 

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Copyright information

© MAIK Nauka 2008

Authors and Affiliations

  • V. A. Mamedov
    • 1
  • A. M. Murtazina
    • 1
  • L. P. Sysoeva
    • 1
  • E. V. Mironova
    • 1
  • Sh. K. Latypov
    • 1
  • A. A. Balandina
    • 1
  • S. F. Kadyrova
    • 1
  • A. T. Gubaidullin
    • 1
  • I. A. Litvinov
    • 1
  1. 1.Arbuzov Institute of Organic and Physical Chemistry, Kazan Research CenterRussian Academy of SciencesKazanRussia

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