Russian Journal of Organic Chemistry

, Volume 44, Issue 2, pp 247–250 | Cite as

4-Functionally-substituted 3-heterylpyrazoles: XIX. 3-aryl-4-(5-isoxazolyl)pyrazoles

  • M. K. Bratenko
  • Yu. V. Kadel’nik
  • V. A. Chornous
  • M. V. Vovk
Article

Abstract

Oximes of 4-(4-pyrazolyl)-3-buten-2-onees obtained by successive reaction of 3-aryl-4-formylpyrazoles with acetone and hydroxylamine at the treatment with iodine suffered an oxidative cyclization yielding 3-aryl-4-(5-isoxazolyl)pyrazoles.

Keywords

Oxime Pyrazole Oxidative Cyclization Pyrazoline Pyrazolyl 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bratenko, M.K., Chornous, V.O., and Vovk, M.V., Zh. Org. Khim., 2007, vol. 43, p. 1213.Google Scholar
  2. 2.
    Elkashef, M.K.-F., Abdel-Magein, F.M.E., and Yassius, M.A., Lieb. Ann., 1974, p. 37.Google Scholar
  3. 3.
    Chernyavichus, V.S., Odinets, A.G., Sausyn’, A.E., Berzinya, A.Ya., and Zolotoyabko, R.M., Khim.-Farm. Zh., 1987, vol. 21, p. 959.Google Scholar
  4. 4.
    Chary, T.J.M., Reddy, Ch.V.N., and Nurthy, A.K., Ind. J. Chem. B., 1992, vol. 31, p. 495.Google Scholar
  5. 5.
    Bratenko, M.K., Chornous, V.O., and Vovk, M.V., Zh. Org. Khim., 2001, vol. 37, p. 591.Google Scholar
  6. 6.
    El-Emary, T.I. and Bakhite, E.A., Pharmazie, 1999, vol. 54, p. 106.Google Scholar
  7. 7.
    Kumar, K.H. and Perumal, P.T., Chem. Lett., 2005, vol. 34, p. 1346.CrossRefGoogle Scholar
  8. 8.
    Mashkovskii, M.D., Lekarstvennye sredstva (Drugs), Moscow: Novaya volna, 2000, vol. 2, pp. 227, 282.Google Scholar
  9. 9.
    Eiden, F. and Patzelt, G., Arch. Pharm., 1986, vol. 319, p. 242.CrossRefGoogle Scholar
  10. 10.
    Bendaas, A., Homdi, M., and Selier, N., J. Heterocycl. Chem., 1999, vol. 36, p. 1291.CrossRefGoogle Scholar
  11. 11.
    Unterhalt, B. and Pindur, U., Arch. Pharm., 1973, vol. 306, p. 586.Google Scholar
  12. 12.
    Unterhalt, B., Arch. Pharm., 1978, vol. 311, p. 265.Google Scholar
  13. 13.
    Alberola, A., Banez, J.M., Carlo, L., Rodriguez, M.T., and Sanudo, M.C., J. Heterocycl. Chem., 1993, vol. 30, p. 467.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2008

Authors and Affiliations

  • M. K. Bratenko
    • 1
  • Yu. V. Kadel’nik
    • 1
  • V. A. Chornous
    • 1
  • M. V. Vovk
    • 2
  1. 1.Bukovina State Medical UniversityChernovtsyUkraine
  2. 2.Institute of Organic ChemistryNational Academy of Sciences of UkraineKievUkraine

Personalised recommendations