Russian Journal of Organic Chemistry

, Volume 43, Issue 12, pp 1754–1756 | Cite as

Chiral copper-Schiff base catalyst for asymmetric henry reaction

  • Yong-guang Gao
  • Na Chen
  • Hua-jiang Wu
  • Xin-sheng Li
Article

Abstract

Five copper-Schiff base complexes were synthesized conveniently from copper(II) acetate monohydrate, salicylaldehydes, and amino alcohols. The complexes were shown to be effective as catalysts in the asymmetric Henry reaction affording nitro alkanols in up to 98% yield with moderate and good enantiomeric excess (up to ee 38.6%).

Keywords

Benzaldehyde Base Complex Nitromethane Salicylaldehydes Amino Alcohol 

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Copyright information

© Pleiades Publishing, Ltd. 2007

Authors and Affiliations

  • Yong-guang Gao
    • 1
  • Na Chen
    • 1
  • Hua-jiang Wu
    • 1
  • Xin-sheng Li
    • 1
  1. 1.Department of ChemistryZhejiang Normal UniversityJinhuaChina

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