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Russian Journal of Organic Chemistry

, Volume 43, Issue 4, pp 615–618 | Cite as

Synthesis of N-(4-oxo-3,4-dihydroquinazolin-3-yl)succinimide and N-(4-oxoquinazolin-3-yl)succinamic acid derivatives based thereon

  • L. A. Shemchuk
  • V. P. Chernykh
  • P. S. Arzumanov
  • D. V. Levashov
  • L. M. Shemchuk
Article

Abstract

The reaction of anthranilic acid hydrazide with diethyl oxalate under microwave irradiation was accompanied by decarboxylation with formation of 3-amino-3,4-dihydroquinazolin-4-one, and acylation of the latter with succinic anhydride gave N-(4-oxo-3,4-dihydroquinazolin-3-yl)siccinimide which was converted into various N-(4-oxo-3,4-dihydroquinazolin-3-yl)succinamic acid derivatives.

Keywords

Imide Succinimide Succinic Anhydride Quinazolinone Propanamide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2007

Authors and Affiliations

  • L. A. Shemchuk
    • 1
  • V. P. Chernykh
    • 1
  • P. S. Arzumanov
    • 1
  • D. V. Levashov
    • 1
  • L. M. Shemchuk
    • 1
  1. 1.National Pharmaceutical UniversityKharkovUkraine

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