Russian Journal of Organic Chemistry

, Volume 43, Issue 3, pp 449–453 | Cite as

Alkylation of pyridinecarbaldehyde oximes with epoxy compounds

  • N. Şen
  • Y. Kar
  • S. Kurbanov
Article

Abstract

O-and N-Alkylation products were obtained by reactions of pyridine-2-,-3-, and-4-carbaldehyde oximes with enantiomerically pure and racemic epoxy compounds (1,2-epoxypropane, 1-phenyl-1,2-epoxyethane, 1-chloro-2,3-epoxypropane, and 1-bromo-2,3-epoxypropane) in the presence of bases and under conditions of phase-transfer catalysis. A series of new amino alcohols was synthesized by condensation of amines with products of O-alkylation of pyridinecarbaldehyde oximes with 1-halo-2,3-epoxypropanes.

Keywords

Oxime Amino Alcohol Metallic Sodium Epoxy Compound Carbaldehyde 

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Copyright information

© Pleiades Publishing, Ltd. 2007

Authors and Affiliations

  • N. Şen
    • 1
  • Y. Kar
    • 2
  • S. Kurbanov
    • 1
  1. 1.Department of ChemistryUniversity of SelcukKonyaTurkey
  2. 2.Department of Chemical EngineeringUniversity of SelcukKonyaTurkey

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