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Russian Journal of Organic Chemistry

, Volume 42, Issue 11, pp 1719–1724 | Cite as

Cycloacylation of N-phenyl-N′-R-thioureas with 3-aryl-2-propenoyl chlorides

  • V. N. Britsun
  • A. N. Esipenko
  • M. O. Lozinskii
Article

Abstract

Cycloalkylation of N-phenyl-N′-R-thiourea with 3-aryl-2-propenoyl chlorides in acetone gives as products 6-aryl-3-phenyl-2-(R-imino)-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-one and their hydrochlorides. The same reaction carried out in acetone in the presence of K2CO3 leads to the formation of 6-aryl-3-phenyl-2-(R-imino)-2,3,5,6-tetrahydro-4H-1,3-thiazin-4-ones, N-(3-aryl-2-propenoyl)-N-phenylthioureas, 3-aryl-2-propenoylanilides, and phenyl isothiocyanate.

Keywords

Compound IIIa Phenyl Isothiocyanate Phenacyl Bromide Anhydrous Acetone Diphenylthiourea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Inc. 2006

Authors and Affiliations

  • V. N. Britsun
    • 1
  • A. N. Esipenko
    • 1
  • M. O. Lozinskii
    • 1
  1. 1.Institute of Organic ChemistryUkrainian Academy of SciencesKiev-94Ukraine

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