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Russian Journal of Organic Chemistry

, Volume 42, Issue 3, pp 396–402 | Cite as

Synthons for biologically active compounds on the basis of naphthalene ozonolysis products

  • O. S. Kukovinets
  • M. I. Kislitsyn
  • R. A. Zainullin
  • M. I. Abdullin
  • F. Z. Galin
Article

Abstract

Ozonolysis of naphthalene in aqueous methanol, followed by the reduction of peroxy compounds thus formed with potassium iodide in the presence of acetic acid, gave 3-methoxy-2-benzofuran-1(3H)-one. In the absence of water, the product was methyl o-formylbenzoate. The latter was used as a synthon for the preparation of aromatic analogs of (2E)-2,6-dimethyloct-2-ene-1,8-diol ethers which are effective juvenoids.

Keywords

Methyl Acetic Ether Methanol Potassium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Inc. 2006

Authors and Affiliations

  • O. S. Kukovinets
    • 1
  • M. I. Kislitsyn
    • 1
  • R. A. Zainullin
    • 2
  • M. I. Abdullin
    • 1
  • F. Z. Galin
    • 2
  1. 1.Bashkir State UniversityUfaRussia
  2. 2.Institute of Organic Chemistry, Ufa Research CenterRussian Academy of SciencesUfaRussia

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