Russian Journal of Organic Chemistry

, Volume 42, Issue 3, pp 396–402 | Cite as

Synthons for biologically active compounds on the basis of naphthalene ozonolysis products

  • O. S. Kukovinets
  • M. I. Kislitsyn
  • R. A. Zainullin
  • M. I. Abdullin
  • F. Z. Galin
Article

Abstract

Ozonolysis of naphthalene in aqueous methanol, followed by the reduction of peroxy compounds thus formed with potassium iodide in the presence of acetic acid, gave 3-methoxy-2-benzofuran-1(3H)-one. In the absence of water, the product was methyl o-formylbenzoate. The latter was used as a synthon for the preparation of aromatic analogs of (2E)-2,6-dimethyloct-2-ene-1,8-diol ethers which are effective juvenoids.

Keywords

Methyl Acetic Ether Methanol Potassium 

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Copyright information

© Pleiades Publishing, Inc. 2006

Authors and Affiliations

  • O. S. Kukovinets
    • 1
  • M. I. Kislitsyn
    • 1
  • R. A. Zainullin
    • 2
  • M. I. Abdullin
    • 1
  • F. Z. Galin
    • 2
  1. 1.Bashkir State UniversityUfaRussia
  2. 2.Institute of Organic Chemistry, Ufa Research CenterRussian Academy of SciencesUfaRussia

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