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Synthesis, Structure, and Biological Activity of Magnesium(II), Zinc(II), Cobalt(II), and Copper(II) Bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates)

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Abstract

The condensation of aryl methyl ketones with diethyl oxalate in the presence of metallic sodium or sodium hydride gave sodium 4-aryl-1-ethoxy-1,4-dioxobut-2-en-2-olates, and metal exchange of the latter with magnesium(II), zinc(II), cobalt(II), and copper(II) salts afforded the corresponding metal bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates). The obtained complexes were tested for antibacterial activity against gram-positive and gram-negative bacteria by the agar diffusion method.

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Correspondence to E. A. Kunavina.

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Russian Text © E.A. Kunavina, V.O. Koz’minykh, A.N. Sizentsov, E.V. Salikova, M.L. Rusyaeva, D.S. Korol’kova, 2019, published in Zhurnal Obshchei Khimii, 2019, Vol. 89, No. 1, pp. 78–82.

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Kunavina, E.A., Koz’minykh, V.O., Sizentsov, A.N. et al. Synthesis, Structure, and Biological Activity of Magnesium(II), Zinc(II), Cobalt(II), and Copper(II) Bis(4-aryl-1-ethoxy-1-oxobutane-2,4-dionates). Russ J Gen Chem 89, 67–70 (2019). https://doi.org/10.1134/S1070363219010122

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  • DOI: https://doi.org/10.1134/S1070363219010122

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