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Synthesis of 5-Aryl-4-acyl-3-hydroxy-1-(2-furylmethyl)-3-pyrrolin-2-ones

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Abstract

Reaction of methyl acylpyruvate with a mixture of aromatic aldehyde and furfurylamine yielded 5-aryl-4-acetyl(benzoyl)-3-hydroxy-1-(2-furylmethyl)-3-pyrrolin-2-ones, the structure of which was established by 1H, 13C NMR and IR spectroscopy methods.

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Correspondence to V. L. Gein.

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Original Russian Text © V.L. Gein, N.V. Nosova, A.P. Shishkin, L.F. Gein, 2018, published in Zhurnal Obshchei Khimii, 2018, Vol. 88, No. 3, pp. 508–511.

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Gein, V.L., Nosova, N.V., Shishkin, A.P. et al. Synthesis of 5-Aryl-4-acyl-3-hydroxy-1-(2-furylmethyl)-3-pyrrolin-2-ones. Russ J Gen Chem 88, 598–601 (2018). https://doi.org/10.1134/S1070363218030337

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  • DOI: https://doi.org/10.1134/S1070363218030337

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